The natural history of type B aortic dissection in patients with PRKG1 mutation c.530G>A (p.Arg177Gln)

ObjectiveThe c.530G>A (p.Arg177Gln) mutation in PRKG1 has been shown to be associated with thoracic aortic aneurysms and dissections. This rare mutation accounts for an estimated 1% of nonsyndromic heritable thoracic aortic disease. We sought to describe the clinical presentation of type B aortic dissection (TBAD), management, and outcomes in patients with this mutation.MethodsThis is a descriptive multi-institutional retrospective study of...