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Sherene Shalhub
University of Washington
DissectionSurgeryCardiologyAortic dissectionMedicine
68Publications
13H-index
670Citations
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Publications 71
Newest
#1Lisa Hysa (UW: University of Washington)H-Index: 1
#2Sara Khor (UW: University of Washington)H-Index: 1
Last. Sherene Shalhub (UW: University of Washington)H-Index: 13
view all 7 authors...
Abstract Objectives Natural history studies of type B aortic dissection (TBAD) commonly report all-cause mortality. Our aim is to determine cause-specific mortality in TBAD and to evaluate the clinical characteristics associated with aortic and non-aortic-related mortality Methods Clinical and administrative records were reviewed for patients with acute TBAD between 1995 and 2017. Demographics, comorbidities, presentation, and initial imaging findings were abstracted. Cause of death was ascertai...
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While a genetic basis for thoracic aortic aneurysm and dissection is well established, little is known about endovascular stent graft therapy (TEVAR) outcomes in patients with family history of aortic disease following Type B acute aortic dissection (TBAD). Patients enrolled in the International
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#1Liz SageH-Index: 1
#2Melissa Russo (Brown University)
Last. Sherene ShalhubH-Index: 13
view all 8 authors...
Abstract Objective Vascular Ehlers-Danlos syndrome (vEDS) is a rare, syndromic, heritable condition with life-threatening complications that include aortic and arterial aneurysms, dissection, and rupture. This study describes the formation of the vEDS Research Collaborative and methods used for stakeholder engagement. Methods The vEDS Research Collaborative was established with an engagement award from the Patient-Centered Outcomes Research Institute to create a framework for a patient-researche...
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#1Sherene Shalhub (UW: University of Washington)H-Index: 13
#2Mary J. Roman (Cornell University)H-Index: 91
Last. Dianna M. Milewicz (University of Texas Health Science Center at Houston)H-Index: 58
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Abstract Background To investigate clinical course of patients with TBAD occurring at a young age with confirmed or suspected heritable thoracic aortic disease Methods Individuals with TBAD occurring at an age Results A total of 150 individuals met inclusion criteria (mean age of TBAD 36.9+9 years): 73 MFS TBAD, 42 FTBAD, and 35 sporadic TBAD. The cohort of sporadic TBAD had more males (71.4%) and less individuals of European descent (51.4%) compared to MFS TBAD (57.5% male, 84.9% European desce...
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#1Sherene Shalhub (UW: University of Washington)H-Index: 13
#2Peter H. Byers (UW: University of Washington)H-Index: 70
Last. Karen Woo (UCLA: University of California, Los Angeles)H-Index: 10
view all 24 authors...
Abstract Objective Vascular Ehlers-Danlos syndrome (vEDS) is a rare disorder and 1 of 13 types of EDS. The syndrome results in aortic and arterial aneurysms and dissections at a young age. Diagnosis is confirmed with molecular testing via skin biopsy or genetic testing for COL3A1 pathogenic variants. We describe a multi-institutional experience in the diagnosis of vEDS from 2000 to 2015. Methods This is a multi-institutional cross-sectional retrospective study of individuals with vEDS. The insti...
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#1Sherene Shalhub (UW: University of Washington)H-Index: 13
#2Liz Sage (UW: University of Washington)H-Index: 1
view all 9 authors...
Abstract Objective Patient centered research requires active engagement of patients. The Vascular Ehlers-Danlos Syndrome (vEDS) research collaborative was established to ascertain patient-centered vEDS research priorities and to engage affected individuals as research partners. Evaluation of access to information and interest in research among individuals with vEDS was the first step undertaken as part of this work. Methods A 28 question survey was created to evaluate four domains of interest: D...
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#1Nicole K. Zern (UW: University of Washington)H-Index: 1
#2Sherene Shalhub (UW: University of Washington)H-Index: 13
Last. Kristine E. Calhoun (UW: University of Washington)H-Index: 14
view all 4 authors...
1 CitationsSource
#1Sherene Shalhub (UW: University of Washington)H-Index: 13
#2Peter H. Byers (UW: University of Washington)H-Index: 70
Last. Karen Woo (UCLA: University of California, Los Angeles)H-Index: 10
view all 24 authors...
Abstract Objective Vascular Ehlers-Danlos syndrome (vEDS) is a rare connective tissue disorder owing to pathogenic variants in COL3A1 that lead to impaired type III collagen production. We aim to describe the contemporary multi-institutional experience of aortic and arterial pathology in individuals with vEDS, to evaluate disease patterns and refine management recommendations. Methods This cross-sectional, retrospective study of individuals with genetically confirmed vEDS was conducted between 2...
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#1Jacob Wilkerson (UW: University of Washington)
#2Matthew Napierala (UW: University of Washington)
Last. Winston J. Warme (UW: University of Washington)H-Index: 21
view all 4 authors...
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#1Matthew A. Bartek (UW: University of Washington)H-Index: 2
#2Larry Kessler (UW: University of Washington)H-Index: 23
Last. Sherene Shalhub (UW: University of Washington)H-Index: 13
view all 5 authors...
Abstract Objective Management of abdominal aortic aneurysms (AAA) has undergone considerable advances over the last two decades. Our aim was to evaluate AAA-related mortality trends in Washington State over a 21-year period and to assess variation in AAA-related mortality by sex, race, and county over the same time period. We hypothesized that a significant decrease in AAA-related mortality in Washington State would be noted. Methods Death certificate records were obtained from the Washington St...
2 CitationsSource
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