Antibody-free digital influenza virus counting based on neuraminidase activity

Volume: 9, Issue: 1
Published: Jan 31, 2019
Abstract
There is large demand for a quantitative method for rapid and ultra-sensitive detection of the influenza virus. Here, we established a digital influenza virus counting (DIViC) method that can detect a single virion without antibody. In the assay, a virion is stochastically entrapped inside a femtoliter reactor array device for the fluorogenic assay of neuraminidase, and incubated for minutes. By analyzing 600,000 reactors, the practical limit of...
Paper Details
Title
Antibody-free digital influenza virus counting based on neuraminidase activity
Published Date
Jan 31, 2019
Volume
9
Issue
1
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