Original paper
Venous endothelin modulates responsiveness of cardiac sympathetic axons to arterial semaphorin
Abstract
Developing neurons of the peripheral nervous system reach their targets via cues that support directional growth, a process known as axon guidance. In investigating how sympathetic axons reach the heart in mice, we discovered that a combination of guidance cues are employed in sequence to refine axon outgrowth, a process we term second-order guidance. Specifically, endothelin-1 induces sympathetic neurons expressing the receptor Ednra to project...
Paper Details
Title
Venous endothelin modulates responsiveness of cardiac sympathetic axons to arterial semaphorin
Published Date
Feb 8, 2019
Journal
Volume
8
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Notes
History