Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies
Abstract
Chronic kidney disease (CKD) affects ~10% of the global population, with considerable ethnic differences in prevalence and aetiology. We assemble genome-wide association studies of estimated glomerular filtration rate (eGFR), a measure of kidney function that defines CKD, in 312,468 individuals of diverse ancestry. We identify 127 distinct association signals with homogeneous effects on eGFR across ancestries and enrichment in genomic...
Paper Details
Title
Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies
Published Date
Jan 3, 2019
Journal
Volume
10
Issue
1
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