Inconclusive evidence for optimal preterm birth prevention

Preventing preterm birth is a laudable aim, given its enormous clinical and economic impact on individuals and society. There is a remarkable lack of consensus as to optimal preventative strategies. Prophylactic therapies are increasingly used, but their relative merits remain unclear. Vaginal cerclage has been in common clinical practice since the 1970s, but more recently, progesterone has gained popularity. The pessary, which has the advantage...