Association of Antipsychotic Treatment With Risk of Unexpected Death Among Children and Youths

Importance

Children and youths who are prescribed antipsychotic medications have multiple, potentially fatal, dose-related cardiovascular, metabolic, and other adverse events, but whether or not these medications are associated with an increased risk of death is unknown.

Objective

To compare the risk of unexpected death among children and youths who are beginning treatment with antipsychotic or control medications.

Design,...