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JAMA Psychiatry
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15.92
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Papers 1742
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#1Annie Kathuria (MIT: Massachusetts Institute of Technology)H-Index: 4
#2Kara Lopez-Lengowski (MIT: Massachusetts Institute of Technology)H-Index: 1
Last. Rakesh KarmacharyaH-Index: 10
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Importance Three-dimensional cerebral organoids generated from patient-derived induced pluripotent stem cells (iPSCs) may be used to interrogate cellular-molecular underpinnings of schizophrenia. Objective To determine transcriptomic profiles and functional characteristics of cerebral organoids from patients with schizophrenia using gene expression studies, complemented with investigations of mitochondrial function through measurement of real-time oxygen consumption rate, and functional studies ...
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#1Stefan G. Hofmann (BU: Boston University)H-Index: 74
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#1Kenneth S. Kendler (VCU: Virginia Commonwealth University)H-Index: 161
#2Henrik Ohlsson (Lund University)H-Index: 24
Last. Kristina SundquistH-Index: 48
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Importance Information about how risk for bipolar disorder is transmitted across generations and how parental risk for bipolar disorder relates to their children’s risk for schizophrenia and major depression is limited. Objective To evaluate the sources of parent-offspring transmission of bipolar disorder and its familial cross-generational association with schizophrenia and major depression. Design, Setting, and Participants Parents and offspring (born 1960-1990) from 4 family types were ascert...
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#1Dominic A. Sisti (UPenn: University of Pennsylvania)H-Index: 10
#2J. John Mann (Columbia University)H-Index: 142
Last. Maria A. Oquendo (UPenn: University of Pennsylvania)H-Index: 51
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#1Pim Cuijpers (PHRI: Public Health Research Institute)H-Index: 104
#2Eirini Karyotaki (PHRI: Public Health Research Institute)H-Index: 16
Last. John R. Weisz (Harvard University)H-Index: 93
view all 8 authors...
Importance It is not clear whether psychotherapies for depression have comparable effects across the life span. Finding out is important from a clinical and scientific perspective. Objective To compare the effects of psychotherapies for depression between different age groups. Data Sources Four major bibliographic databases (PubMed, PsychINFO, Embase, and Cochrane) were searched for trials comparing psychotherapy with control conditions up to January 2019. Study Selection Randomized trials compa...
1 CitationsSource
#1Kenneth S. Kendler (VCU: Virginia Commonwealth University)H-Index: 161
#2Henrik Ohlsson (Lund University)H-Index: 24
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#1Patrick D. McGorry (University of Melbourne)H-Index: 109
#2Barnaby Nelson (University of Melbourne)H-Index: 44
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#1Gemma Lewis (UCL: University College London)H-Index: 3
#2Jennifer Dykxhoorn (UCL: University College London)H-Index: 4
Last. James B. Kirkbride (UCL: University College London)H-Index: 30
view all 7 authors...
Importance Being born or raised in more densely populated or deprived areas is associated with increased risk of nonaffective psychosis in adulthood, but few studies to date have examined the role of general cognitive ability in these associations. Objective To investigate whether lower IQ contributed to the association between population density or deprivation and nonaffective psychosis (mediation) and whether these associations were stronger in people with lower IQ (effect modification). Desig...
1 CitationsSource
#1Jay H. Shore (Anschutz Medical Campus)H-Index: 18
Source
Importance Detection, prognosis, and indicated interventions in individuals at clinical high risk for psychosis (CHR-P) are key components of preventive psychiatry. Objective To provide a comprehensive, evidence-based systematic appraisal of the advancements and limitations of detection, prognosis, and interventions for CHR-P individuals and to formulate updated recommendations. Evidence Review Web of Science, Cochrane Central Register of Reviews, and Ovid/PsychINFO were searched for articles pu...
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