Review paper
RUNX1‐dependent mechanisms in biological control and dysregulation in cancer
Abstract
The RUNX1 transcription factor has recently been shown to be obligatory for normal development. RUNX1 controls the expression of genes essential for proper development in many cell lineages and tissues including blood, bone, cartilage, hair follicles, and mammary glands. Compromised RUNX1 regulation is associated with many cancers. In this review, we highlight evidence for RUNX1 control in both invertebrate and mammalian development and recent...
Paper Details
Title
RUNX1‐dependent mechanisms in biological control and dysregulation in cancer
Published Date
Dec 4, 2018
Volume
234
Issue
6
Pages
8597 - 8609
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