Transcriptomic landscape of the blastema niche in regenerating adult axolotl limbs at single-cell resolution
Abstract
Regeneration of complex multi-tissue structures, such as limbs, requires the coordinated effort of multiple cell types. In axolotl limb regeneration, the wound epidermis and blastema have been extensively studied via histology, grafting, and bulk-tissue RNA-sequencing. However, defining the contributions of these tissues is hindered due to limited information regarding the molecular identity of the cell types in regenerating limbs. Here we...
Paper Details
Title
Transcriptomic landscape of the blastema niche in regenerating adult axolotl limbs at single-cell resolution
Published Date
Dec 4, 2018
Journal
Volume
9
Issue
1
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