Metabolomics predicts the pharmacological profile of new psychoactive substances

The unprecedented proliferation of new psychoactive substances (NPS) threatens public health and challenges drug policy. Information on NPS pharmacology and toxicity is, in most cases, unavailable or very limited and, given the large number of new compounds released on the market each year, their timely evaluation by current standards is certainly challenging.We present here a metabolomics-targeted approach to predict the pharmacological profile...