Original paper
Precise A•T to G•C base editing in the zebrafish genome
Abstract
Base editors are a class of genome editing tools with the ability to efficiently induce point mutations in genomic DNA, without inducing double-strand breaks or relying on homology-direct repair as in other such technologies. Recently, adenine base editors (ABEs) have been developed to mediate the conversion of A•T to G•C in genomic DNA of human cells, mice, and plants. Here, we investigated the activity and efficiency of several adenine base...
Paper Details
Title
Precise A•T to G•C base editing in the zebrafish genome
Published Date
Nov 20, 2018
Journal
Volume
16
Issue
1
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Notes
History