Effect of novel internal structures on printability and drug release behavior of 3D printed tablets

Semi-solid extrusion (SSE) 3D printing is an innovative and promising method that is suitable for the fabrication of personalized dosage forms of tablets. The aim of this study is to develop and evaluate the effectiveness of SSE 3D printed tablets with novel internal structures. Twelve types of 3D printed tablets with pre-designed structures were developed. Glipizide was selected as the model drug and three different concentrations of the HPMC...