Review paper
Learning from other autoimmunities to understand targeting of B cells to control multiple sclerosis
Abstract
Although many suspected autoimmune diseases are thought to be T cell-mediated, the response to therapy indicates that depletion of B cells consistently inhibits disease activity. In multiple sclerosis, it appears that disease suppression is associated with the long-term reduction of memory B cells, which serves as a biomarker for disease activity in many other CD20+ B cell depletion-sensitive, autoimmune diseases. Following B cell depletion, the...
Paper Details
Title
Learning from other autoimmunities to understand targeting of B cells to control multiple sclerosis
Published Date
Sep 12, 2018
Journal
Volume
141
Issue
10
Pages
2834 - 2847
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History