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Clinical features associated with an increased risk for alcohol use disorders among family members.

Published on Sep 1, 2018in Psychology of Addictive Behaviors2.97
· DOI :10.1037/adb0000388
Richard F. Farmer15
Estimated H-index: 15
(Oregon Research Institute),
John R. Seeley79
Estimated H-index: 79
(UO: University of Oregon)
+ 5 AuthorsPeter M. Lewinsohn94
Estimated H-index: 94
(Oregon Research Institute)
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Published on Jul 20, 2016
Espen Røysamb36
Estimated H-index: 36
,
Kristian Tambs48
Estimated H-index: 48
During the last fifty years more than 2700 twin studies have been published, examining the etiology of a high number of traits. Twin studies enable investigation of both genetic and environmental effects, and thereby also examination of causal factors involved in human traits and disorders. The beauty of twin studies resides in the potential of studying the unobserved by the logic of a design. The aim of this article is to outline central theoretical foundations and possible limitations, and to ...
Published on Jul 1, 2016in Drug and Alcohol Dependence3.47
Kenneth S. Kendler152
Estimated H-index: 152
(VCU: Virginia Commonwealth University),
Henrik Ohlsson21
Estimated H-index: 21
(Lund University)
+ 3 AuthorsKristina Sundquist47
Estimated H-index: 47
(Lund University)
Abstract Background Alcohol Use Disorder (AUD) is clinically heterogeneous. Using a large epidemiological sample ascertained via public registries, is it possible to identify clinical and historical features of AUD that reflect familial risk? Methods Using registration in national medical, legal or pharmacy registries, we identified four kinds of relative pairs (n = 683,223) starting with a proband with AUD: cousins, half-siblings, full-siblings and monozygotic cotwins. Using linear hazard regre...
Published on Mar 1, 2015in JAMA Psychiatry15.92
Kenneth S. Kendler152
Estimated H-index: 152
(VCU: Virginia Commonwealth University),
Jianguang Ji30
Estimated H-index: 30
(Lund University)
+ 3 AuthorsKristina Sundquist47
Estimated H-index: 47
(Stanford University)
Importance Alcohol use disorder (AUD) runs strongly in families. It is unclear to what extent the cross-generational transmission of AUD results from genetic vs environmental factors. Objective To determine to what extent genetic and environmental factors contribute to the risk for AUD. Design, Setting, and Participants Follow-up in 8 public data registers of adoptees, their biological and adoptive relatives, and offspring and parents from stepfamilies and not-lived-with families in Sweden. In t...
Published on Mar 1, 2014in Clinical psychological science
Avshalom Caspi146
Estimated H-index: 146
,
Renate Houts41
Estimated H-index: 41
(Duke University)
+ 8 AuthorsRichie Poulton86
Estimated H-index: 86
(University of Otago)
Mental disorders traditionally have been viewed as distinct, episodic, and categorical conditions. This view has been challenged by evidence that many disorders are sequentially comorbid, recurrent/chronic, and exist on a continuum. Using the Dunedin Multidisciplinary Health and Development Study, we examined the structure of psychopathology, taking into account dimensionality, persistence, co-occurrence, and sequential comorbidity of mental disorders across 20 years, from adolescence to midlife...
Published on Feb 1, 2014in Alcoholism: Clinical and Experimental Research3.23
Angela M. Haeny4
Estimated H-index: 4
(MU: University of Missouri),
Andrew K. Littlefield21
Estimated H-index: 21
(MU: University of Missouri),
Kenneth J. Sher71
Estimated H-index: 71
(MU: University of Missouri)
Lifetime prevalence of alcohol use disorders (AUDs; alcohol abuse and/or alcohol dependence [AD]) is derived from cross-sectional studies (e.g., Epidemiological Catchment Area study [ECA; Robins and Regier, 1991], the National Comorbidity Survey [NCS; Kessler et al., 1994], the National Comorbidity Survey—Replication [NCS-R; Kessler et al., 2005], the National Longitudinal Alcohol Epidemiological Survey [Grant et al., 1994a, b, 2004], and the National Epidemiological Survey on Alcohol Related Co...
Published on Dec 1, 2013in Addiction6.85
Marlous Tuithof10
Estimated H-index: 10
,
M. ten Have49
Estimated H-index: 49
+ 2 AuthorsR. de Graaf83
Estimated H-index: 83
To establish the 3-year persistency rate of alcohol use disorder (AUD) and its predictors, and to examine drinking patterns of recently remitted individuals. The Netherlands Mental Health Survey and Incidence Study-2 (NEMESIS-2) surveyed a nationally representative sample of adults (aged 18-64 years) at baseline (response = 65.1%) and 3-year follow-up (response = 80.4%). People with AUD at baseline, as defined by DSM-5 (n = 198). AUD, drinking patterns and mental disorders were assessed using th...
Published on Sep 1, 2013in Behavior Genetics2.31
Melissa A. Munn-Chernoff10
Estimated H-index: 10
(WashU: Washington University in St. Louis),
Kristin M. von Ranson19
Estimated H-index: 19
(U of C: University of Calgary)
+ 3 AuthorsKelly L. Klump53
Estimated H-index: 53
(MSU: Michigan State University)
Little research has investigated whether the twin representativeness assumption (that results from twin research generalize to singletons) holds for eating pathology and internalizing symptoms. This study compared disordered eating, depression, and anxiety among young adult female twins versus singletons. Participants included 292 twins and 997 singletons in three samples. Questionnaires included the Minnesota Eating Behavior Survey, Eating Disorder Examination Questionnaire, Beck Depression Inv...
Published on Jul 1, 2013in Comprehensive Psychiatry2.59
Richard F. Farmer15
Estimated H-index: 15
(Oregon Research Institute),
John R. Seeley79
Estimated H-index: 79
(Oregon Research Institute)
+ 2 AuthorsPeter M. Lewinsohn94
Estimated H-index: 94
(Oregon Research Institute)
Abstract Hierarchical models of psychopathology based on substantial numbers of lifetime diagnostic categories have not been sufficiently evaluated, even though such models have relevance for theories of disorder etiology, course, or prognosis. In this research, a hierarchical component model of 16 Axis I disorders is derived, and model elements are evaluated in terms of their ability to demonstrate distinct associations with several clinically-relevant variables. Participants were 816 randomly ...
Published on Mar 1, 2013in Journal of Studies on Alcohol and Drugs2.58
Mary Waldron18
Estimated H-index: 18
(IU: Indiana University Bloomington),
Kathleen K. Bucholz78
Estimated H-index: 78
+ 2 AuthorsAndrew C. Heath111
Estimated H-index: 111
Objective:We examined history of alcoholism and occurrence and timing of separation in parents of a female twin cohort.Method:Parental separation (never-together; never-married cohabitants who separated; married who separated) was predicted from maternal and paternal alcoholism in 326 African ancestry (AA) and 1,849 European/other ancestry (EA) families. Broad (single-informant, reported in abstract) and narrow (self-report or two-informant) measures of alcoholism were compared.Results:Parental ...
Published on Jan 1, 2013in Journal of Abnormal Psychology5.52
Richard F. Farmer15
Estimated H-index: 15
,
Derek B. Kosty14
Estimated H-index: 14
+ 2 AuthorsPeter M. Lewinsohn94
Estimated H-index: 94
Longitudinal data from representative birth cohorts on the aggregation of psychiatric disorders, or the cumulative number of unique diagnosed disorders experienced by persons within a circumscribed period, are limited. Consequently, risk factors for and psychosocial implications of lifetime disorder aggregation in the general population remain largely unknown. This research evaluates the incidence, predictors, and psychosocial sequela of lifetime disorder aggregation from childhood through age 3...
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