LPA variants, risk of coronary disease, and estimated clinical benefit of lipoprotein(a) lowering therapies: A mendelian randomization analysis
Abstract
Aim: AIMS: Genetic studies suggest Lp(a) is causally associated with the risk of CHD, but randomized trials have not provided evidence that lowering Lp(a) reduces CHD risk. We sought to estimate by how much Lp(a) mass must be lowered to produce a clinically meaningful reduction in CHD...
Paper Details
Title
LPA variants, risk of coronary disease, and estimated clinical benefit of lipoprotein(a) lowering therapies: A mendelian randomization analysis
Published Date
Aug 1, 2018
Journal
Volume
275
Pages
e4 - e4
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Notes
History