Regulation of T Follicular Helper Cells in Islet Autoimmunity
Abstract
T follicular helper (TFH) cells are an integral part of humoral immunity by providing help to B cells to produce high-affinity antibodies. The TFH precursor compartment circulates in the blood and TFH cell dysregulation is implied in various autoimmune diseases including type 1 diabetes (T1D). Symptomatic T1D is preceded by a preclinical phase (indicated by the presence of islet autoantibodies) with a highly variable progression time to the...
Paper Details
Title
Regulation of T Follicular Helper Cells in Islet Autoimmunity
Published Date
Jul 23, 2018
Journal
Volume
9
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