Antibody-Mediated Rejection With and Without HLA Donor-Specific Antibodies in Kidney-Transplantation

Background Correlation between antibody-mediated damage (AMR) and HLA donor-specific antibodies (DSA) is strong but imperfect in kidney transplant (KT) recipients. We reviewed histopathology and HLA DSA in AMR patients and compared them with those with only interstitial fibrosis and tubular atrophy (IFTA) or no abnormalities. Methods Retrospective assessment of patients with biopsies (Banff’13) and serum samples (pre- and postransplant) tested...