Selegiline reduces adiposity induced by high-fat, high-sucrose diet in male rats

Background and Purpose Incidence and severity of obesity are increasing worldwide, however, efficient and safe pharmacological treatments are not yet available. Certain MAO inhibitors reduce body weight, although their effects on metabolic parameters have not been investigated. Here, we have assessed effects of a widely used, selective MAO‐B inhibitor, selegiline, on metabolic parameters in a rat model of diet‐induced obesity. Experimental...