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Csilla Terézia Nagy
Semmelweis University
7Publications
3H-index
37Citations
Publications 7
Newest
#1Krisztina Lajtai (Semmelweis University)
#2Csilla Terézia Nagy (Semmelweis University)H-Index: 3
Last.Szabolcs Várbíró (Semmelweis University)H-Index: 13
view all 13 authors...
Aim: We aimed to examine the alterations of the insulin signaling pathway, autophagy, nitrative stress and the effect of vitamin D supplementation in the liver and ovaries of vitamin D deficient hyperandrogenic rats. Methods: Female Wistar rats received eight weeks of transdermal testosterone treatment and lived on a low vitamin D diet (D–T+). Vitamin D supplementation was achieved by oral administration of vitamin D3 (D+T+). Sham-treated (D+T–) and vitamin D deficient animals (D–T–) served as c...
#1Zsófia Onódi (Semmelweis University)H-Index: 4
#2Csilla Pelyhe (Semmelweis University)H-Index: 2
Last.Zoltán Giricz (Semmelweis University)H-Index: 24
view all 10 authors...
Background: Extracellular vesicles (EVs) isolated from blood plasma are extensively investigated both as biomarkers and therapeutics. However, efficient isolation of high-purity EVs from blood plasma in quantities sufficient for in-vivo experiments is a great challenge. Thus, the aim of this study was to develop an isolation method to separate the majority of EVs from major impurities such as lipoprotein particles and abundant plasma proteins albumin and fibrinogen. Methods: Rat blood samples we...
#1Csilla Terézia Nagy (Semmelweis University)H-Index: 3
#2Gábor Koncsos (Semmelweis University)H-Index: 4
Last.Péter Ferdinandy (Semmelweis University)H-Index: 54
view all 24 authors...
#1Zoltán Giricz (Semmelweis University)H-Index: 24
#2Zoltán Varga (Semmelweis University)H-Index: 18
Last.Péter Ferdinandy (Semmelweis University)H-Index: 54
view all 8 authors...
Abstract Aims Chloramphenicol (CAP), a broad spectrum antibiotic, was shown to protect the heart against ischemia/reperfusion (I/R) injury. CAP also induces autophagy, however, it is not known whether CAP-induced cardioprotection is mediated by autophagy. Therefore, here we aimed to assess whether activation of autophagy is required for the infarct size limiting effect of CAP and to identify which component of CAP-induced autophagy contributes to cardioprotection against I/R injury. Main methods...
#1Laura Kiscsatári (University of Szeged)H-Index: 2
#2Zoltán Varga (University of Szeged)H-Index: 24
Last.Anikó Görbe (Semmelweis University)H-Index: 18
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Abstract Despite the great clinical significance of radiation-induced cardiac damage, experimental investigation of its mechanisms is an unmet need in medicine. Beneficial effects of growth hormone-releasing hormone (GHRH) agonists in regeneration of the heart have been demonstrated. The aim of this study was the evaluation of the potential of modern GHRH agonistic analogs in prevention of radiation damage in an in vitro cardiac myocyte-based model. Cultures of cardiac myocytes isolated from new...
#1Tamás Baranyai (Semmelweis University)H-Index: 9
#2Rinesh GodfreyH-Index: 3
Last.Roberto Pedrinelli (UniPi: University of Pisa)H-Index: 35
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# 11 Acute hyperglycemia abolishes cardioprotection by remote ischemic perconditioning {#article-title-2} Background: Remote ischemic perconditioning (RIPerC) has a promising therapeutic value to improve prognosis of acute myocardial infarction. Chronic comorbidities such as diabetes are known to interfere with conditioning interventions by modulating cardioprotective signaling pathways, such as e.g. autophagy. However, the effect of acute hyperglycemia on RIPerC has not been studied so far. The...
#1Tamás Baranyai (Semmelweis University)H-Index: 9
#2Csilla Terézia Nagy (Semmelweis University)H-Index: 3
Last.Zoltán Giricz (Semmelweis University)H-Index: 24
view all 9 authors...
Background Remote ischemic perconditioning (RIPerC) has a promising therapeutic insight to improve the prognosis of acute myocardial infarction. Chronic comorbidities such as diabetes are known to interfere with conditioning interventions by modulating cardioprotective signaling pathways, such as e.g., mTOR pathway and autophagy. However, the effect of acute hyperglycemia on RIPerC has not been studied so far. Therefore, here we investigated the effect of acute hyperglycemia on cardioprotection ...
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