Association of CREBRF Variants with BMI and Diabetes in Pacific Islanders
Abstract
A recent genome-wide association study (GWAS) in Samoans (a Polynesian population) identified strong associations of CREBRF variants with BMI. The G allele at rs12513649 (frequency=25.8%) was associated with ∼1.3 kg/m2 higher BMI per copy, as was the Gln allele at rs373863828 (which codes for an ArgGln substitution). The Gln allele at rs373863828 has frequency of 25.9% in Samoans and is rare in most global populations, although it has been...
Paper Details
Title
Association of CREBRF Variants with BMI and Diabetes in Pacific Islanders
Published Date
Jul 1, 2018
Journal
Volume
67
Issue
Supplement_1
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