KRAS: Reasons for optimism in lung cancer
Abstract
Despite being the most frequent gain-of-function genetic alteration in human cancer, KRAS mutation has to date offered only limited potential as a prognostic and predictive biomarker. Results from the phase III SELECT-1 trial in non-small cell lung cancer (NSCLC) recently added to a number of historical and more contemporary disappointments in targeting KRAS mutant disease, including farnesyl transferase inhibition and synthetic lethality...
Paper Details
Title
KRAS: Reasons for optimism in lung cancer
Published Date
Aug 1, 2018
Journal
Volume
99
Pages
20 - 27
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