Original paper
ROP: dumpster diving in RNA-sequencing to find the source of 1 trillion reads across diverse adult human tissues
Abstract
High-throughput RNA-sequencing (RNA-seq) technologies provide an unprecedented opportunity to explore the individual transcriptome. Unmapped reads are a large and often overlooked output of standard RNA-seq analyses. Here, we present Read Origin Protocol (ROP), a tool for discovering the source of all reads originating from complex RNA molecules. We apply ROP to samples across 2630 individuals from 54 diverse human tissues. Our approach can...
Paper Details
Title
ROP: dumpster diving in RNA-sequencing to find the source of 1 trillion reads across diverse adult human tissues
Published Date
Feb 15, 2018
Journal
Volume
19
Issue
1
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Notes
History