Sleep apnea in Machado-Joseph disease: a clinical and polysomnographic evaluation

Machado-Joseph disease (MJD) or spinocerebellar ataxia type 3 (SCA3) is the most common type of autosomal dominant spinocerebellar ataxia (SCA). Sleep disorders have been described as frequent non-motor symptoms in MJD, and with marked impairment on quality of life. However, few studies have evaluated the frequency and characteristics of sleep apnea in MJD.This study analyzed the prevalence of sleep apnea in 47 patients with MJD by using...