Review paper
Causes and Consequences of Hematopoietic Stem Cell Heterogeneity
Abstract
Blood and immune cells derive from multipotent hematopoietic stem cells (HSCs). Classically, stem and progenitor populations have been considered discrete homogeneous populations. However, recent technological advances have revealed significant HSC heterogeneity, with evidence for early HSC lineage segregation and the presence of lineage-biased HSCs and lineage-restricted progenitors within the HSC compartment. These and other findings challenge...
Paper Details
Title
Causes and Consequences of Hematopoietic Stem Cell Heterogeneity
Published Date
May 1, 2018
Journal
Volume
22
Issue
5
Pages
627 - 638
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