The pig as a preclinical model for predicting oral bioavailability and in vivo performance of pharmaceutical oral dosage forms: a PEARRL reviewPublished on Apr 1, 2019in Journal of Pharmacy and Pharmacology2.39· DOI :10.1111/jphp.12912Copy DOILaura J. Henze2Estimated H-index: 2 (UCC: University College Cork), Niklas J. Koehl3Estimated H-index: 3 (UCC: University College Cork)+ 3 AuthorsBrendan T. Griffin19Estimated H-index: 19 (UCC: University College Cork)Request Full-textCiteAbstract
References123NewestExploring gastric emptying rate in minipigs: Effect of food type and pre-dosing of metoclopramideJun 1, 2018·European Journal of Pharmaceutical Sciences3.53#1Laura J. Henze (UCC: University College Cork)H-Index: 2#2Brendan T. Griffin (UCC: University College Cork)H-Index: 19Last.René Holm (Johnson & Johnson)H-Index: 30view all 6 authors...5 CitationsSourceCiteSaveA Model-Based Approach To Assessing the Importance of Intracellular Binding Sites in Doxorubicin DispositionMar 6, 2017·Molecular Pharmaceutics4.40#1Ilse R. DubbelboerH-Index: 4#2Elsa LilienbergH-Index: 5Last.Hans LennernäsH-Index: 56view all 4 authors...7 CitationsSourceCiteSaveConsiderations for the development of in vitro dissolution tests to reduce or replace preclinical oral absorption studiesMar 1, 2017·European Journal of Pharmaceutical Sciences3.53#1E. Gringard (University of Bath)H-Index: 1#2Robert Taylor (East Sussex County Council)H-Index: 5Last.Nikoletta Fotaki (University of Bath)H-Index: 15view all 5 authors...9 CitationsSourceCiteSaveIn vitro dissolution models for the prediction of in vivo performance of an oral mesoporous silica formulationMar 1, 2017·Journal of Controlled Release7.90#1Carol A. McCarthy (UCC: University College Cork)H-Index: 3#2Waleed Faisal (UCC: University College Cork)H-Index: 6Last.Abina M. Crean (UCC: University College Cork)H-Index: 17view all 8 authors...10 CitationsSourceCiteSaveA Dual-Biotic System for the Concurrent Delivery of Antibiotics and Probiotics: In Vitro, Ex Vivo, In Vivo and In Silico Evaluation and CorrelationDec 1, 2016·Pharmaceutical Research3.90#1Mershen Govender (University of the Witwatersrand)H-Index: 3#2Yahya E. Choonara (University of the Witwatersrand)H-Index: 30Last.Viness Pillay (University of the Witwatersrand)H-Index: 35view all 7 authors...3 CitationsSourceCiteSaveBuccal absorption of diazepam is improved when administered in bioadhesive tablets-An in vivo study in conscious Göttingen mini-pigs.Dec 1, 2016·International Journal of Pharmaceutics4.21#1Emil Meng-Lund (UCPH: University of Copenhagen)H-Index: 6#2Jette Jacobsen (UCPH: University of Copenhagen)H-Index: 5Last.René Holm (UCPH: University of Copenhagen)H-Index: 30view all 5 authors...11 CitationsSourceCiteSaveCharacterization of Pharmacokinetics in the Göttingen Minipig with Reference Human Drugs: An In Vitro and In Vivo Approach.Nov 1, 2016·Pharmaceutical Research3.90#1Floriane Lignet (Hoffmann-La Roche)H-Index: 2#2Eva Sherbetjian (Hoffmann-La Roche)H-Index: 1Last.Neil Parrott (Hoffmann-La Roche)H-Index: 22view all 8 authors...5 CitationsSourceCiteSaveEffects of gastric pH on oral drug absorption: In vitro assessment using a dissolution/permeation system reflecting the gastric dissolution processApr 1, 2016·European Journal of Pharmaceutics and Biopharmaceutics4.71#1Makoto Kataoka (Setsunan University)H-Index: 19#2Miho Fukahori (Setsunan University)H-Index: 1Last.Shinji Yamashita (Setsunan University)H-Index: 38view all 7 authors...13 CitationsSourceCiteSaveThe Use of Minipigs for Preclinical Safety Assessment by the Pharmaceutical Industry: Results of an IQ DruSafe Minipig SurveyApr 1, 2016·Toxicologic Pathology1.38#1Curtis Colleton (BMS: Bristol-Myers Squibb)H-Index: 1#2David Brewster (Vertex Pharmaceuticals)H-Index: 4Last.Michael J. Graziano (BMS: Bristol-Myers Squibb)H-Index: 26view all 7 authors...11 CitationsSourceCiteSaveUtility of PBPK Absorption Modeling to Guide Modified Release Formulation Development of Gaboxadol, a Highly Soluble Compound With Region-Dependent AbsorptionFeb 1, 2016·Journal of Pharmaceutical Sciences3.20#1Filippos Kesisoglou (MSD: Merck & Co.)H-Index: 16#2Anand Balakrishnan (BMS: Bristol-Myers Squibb)H-Index: 6Last.Kimberly Manser (MSD: Merck & Co.)H-Index: 6view all 3 authors...12 CitationsSourceCiteSave12345678910
Cited By4NewestToward the establishment of a standardized pre-clinical porcine model to predict food effects - case studies on Fenofibrate and Paracetamol#1Laura J. Henze (UCC: University College Cork)H-Index: 2#2Niklas J. Koehl (UCC: University College Cork)H-Index: 3Last.Brendan T. Griffin (UCC: University College Cork)H-Index: 19view all 6 authors...SourceCiteSaveIn Vivo Metabolism of Ibuprofen in Growing Conventional Pigs: A Pharmacokinetic ApproachJun 27, 2019·Frontiers in Pharmacology3.85#1Joske Millecam (UGent: Ghent University)H-Index: 3#2Siegrid De Baere (UGent: Ghent University)H-Index: 24Last.Mathias Devreese (UGent: Ghent University)H-Index: 17view all 4 authors...SourceCiteSaveOral delivery of non-viral nucleic acid-based therapeutics - do we have the guts for this?May 1, 2019·European Journal of Pharmaceutical Sciences3.53#1Caitriona M. O'Driscoll (UCC: University College Cork)H-Index: 31#2Andreas Bernkop-Schnürch (University of Innsbruck)H-Index: 63Last.Vincent JanninH-Index: 19view all 5 authors...2 CitationsSourceCiteSaveApplication of Permeation Enhancers in Oral Delivery of Macromolecules: An UpdateJan 19, 2019·Pharmaceutics#1Sam MaherH-Index: 18#2David J. BraydenH-Index: 37Last.Lisbeth IllumH-Index: 75view all 4 authors...4 CitationsSourceCiteSave1