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Journal of Pharmacy and Pharmacology
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#1Xiao‐Dong Pei (GXNU: Guangxi Normal University)
#2Song‐Qing He (Guangxi Medical University)
Last. Zhi‐Long He (Xida: Guangxi University)
view all 11 authors...
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#1Hong-Ye Zhang (SPU: Shenyang Pharmaceutical University)H-Index: 2
#2Hui-min Huang (Guangxi Medical University)H-Index: 1
Last. Xu-Wen Liu (Guangxi Medical University)H-Index: 3
view all 18 authors...
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#1Xin Liu (Lanzhou University)
#2Shuying Shang (Lanzhou University)
Last. Baoping Shao (Lanzhou University)H-Index: 3
view all 9 authors...
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#1Jiang Xu (USTC: University of Science and Technology of China)
view all 5 authors...
OBJECTIVES: Metformin (MET) has protective effect on diabetic nephropathy (DN). This study aims to demystify the mechanism of MET function in DN. METHODS: Mouse glomerular membrane epithelial cell line SV40-MES-13 was treated with normal or high glucose combined with or without MET. The relationships among H19, miR-143-3p and TGF-beta1 were evaluated by luciferase reporter assay. MTT assay was performed to detect cell proliferation. The levels of inflammatory factors were investigated by enzyme-...
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Endocrinology
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