Original paper
Fingolimod interrupts the cross talk between estrogen metabolism and sphingolipid metabolism within prostate cancer cells
Abstract
Sphingolipids are critical regulators of tumor microenvironments and play an important role in estrogen-dependent cancers. Estrogen and estrogen metabolites were found to be involved in prostate cancer. Fingolimod (FTY720) is a sphingokinase-1 (SphK1) inhibitor with anticancer properties against various tumor cell types. Herein, we investigated the interference of FTY720 with the cross talk between sphingolipid metabolism and estrogen metabolism...
Paper Details
Title
Fingolimod interrupts the cross talk between estrogen metabolism and sphingolipid metabolism within prostate cancer cells
Published Date
Jul 1, 2018
Journal
Volume
291
Pages
77 - 85
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Notes
History