Review paper
Mechanisms of Tolerance Induction by Dendritic Cells In Vivo
Abstract
Dendritic cells (DCs) are a heterogeneous population playing a pivotal role in immune responses and tolerance. DCs promote immune tolerance by participating in the negative selection of autoreactive T cells in the thymus. Furthermore, to eliminate autoreactive T cells that have escaped thymic deletion, DCs also induce immune tolerance in the periphery through various mechanisms. Breakdown of these functions leads to autoimmune diseases....
Paper Details
Title
Mechanisms of Tolerance Induction by Dendritic Cells In Vivo
Published Date
Feb 26, 2018
Journal
Volume
9
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