Original paper
Pervasive Correlated Evolution in Gene Expression Shapes Cell and Tissue Type Transcriptomes
Abstract
The evolution and diversification of cell types is a key means by which animal complexity evolves. Recently, hierarchical clustering and phylogenetic methods have been applied to RNA-seq data to infer cell type evolutionary history and homology. A major challenge for interpreting this data is that cell type transcriptomes may not evolve independently due to correlated changes in gene expression. This nonindependence can arise for several...
Paper Details
Title
Pervasive Correlated Evolution in Gene Expression Shapes Cell and Tissue Type Transcriptomes
Published Date
Jan 23, 2018
Journal
Volume
10
Issue
2
Pages
538 - 552
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Notes
History