Original paper
Randomized, dose-ranging safety trial of cannabidiol in Dravet syndrome
Abstract
Objective
To evaluate the safety and preliminary pharmacokinetics of a pharmaceutical formulation of purified cannabidiol (CBD) in children with Dravet syndrome.Methods
Patients aged 4–10 years were randomized 4:1 to CBD (5, 10, or 20 mg/kg/d) or placebo taken twice daily. The double-blind trial comprised 4-week baseline, 3-week treatment (including titration), 10-day taper, and 4-week follow-up periods. Completers could...Paper Details
Title
Randomized, dose-ranging safety trial of cannabidiol in Dravet syndrome
Published Date
Apr 3, 2018
Journal
Volume
90
Issue
14
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Notes
History