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In their article, Noh and colleagues reported the case of a young gentleman with longstanding lumbago and previous laminectomy with fusion of L4-S1 who developed a low-pressure headache following acupuncture. On examination, the patient had clear fluid extravasating from an acupuncture site in the lower back, suggestive of a transcutaneous CSF leak. A magnetic resonance myelogram confirmed CSF leakage, which was treated with duroplasty with improvement in the patient's headache. Although the pat...
#2J SpillaneH-Index: 8
Last.Aisling CarrH-Index: 10
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Our objective was to evaluate whether IV immunoglobulin (IVIg) increases the risk of thromboembolic events in neurology outpatients with inflammatory neuropathies, as there is conflicting evidence supporting this hypothesis, mainly from non-neurologic cohorts. We investigated this question over 30 months in our cohort of patients with inflammatory neuropathies receiving regular IVIg and found a greater incidence of arterial and venous thromboembolic events than population-based rates determined ...
As many as 10%–15% of patients with frontotemporal dementia (FTD) are known to have concomitant amyotrophic lateral sclerosis (ALS), and this association is mainly with the behavioral variant of FTD. However, some patients with primary progressive aphasia (PPA) have also developed ALS. In their observational cohort of 130 patients with semantic variant (n = 64) or nonfluent variant (n = 66) PPA, Tan and colleagues sought to better characterize the relationship between PPA and ALS. Of the include...
#1José GazullaH-Index: 10
#2Isidro FerrerH-Index: 56
Last.José BercianoH-Index: 48
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In their article, Tan et al.1 highlighted the association between primary nonfluent aphasia (nfvPPA), the semantic subtype of primary progresssive aphasia (PPA), and amyotrophic lateral sclerosis (ALS), which may also be hereditary.
We read with interest the article by Noh et al.,1 which sounded a warning against acupuncture manipulation. However, we still have several doubts about this case.
#1Jessica Rice (OHSU: Oregon Health & Science University)H-Index: 1
#2Randall L. Woltjer (OHSU: Oregon Health & Science University)H-Index: 38
Last.Vijayshree Yadav (OHSU: Oregon Health & Science University)H-Index: 23
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Primary angiitis of the CNS (PACNS) is a rare small or medium vessel vasculitis confined to the CNS.
#1Paulo Victor Sgobbi de Souza (UNIFESP: Federal University of São Paulo)H-Index: 8
#2Bruno de Mattos Lombardi Badia (UNIFESP: Federal University of São Paulo)
Last.Acary Souza Bulle Oliveira (UNIFESP: Federal University of São Paulo)H-Index: 19
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An 11-year-old Brazilian boy presented with worsening left thigh weakness. At age 2 years, he presented with left lower limb weakness after 4 days of a severe asthma episode. Examination showed amyotrophy, weakness, and areflexia of the left lower limb (figure). Spine MRI and CSF analysis (including serology and PCR for herpesvirus, enterovirus, and arbovirus) were unremarkable. Neurophysiologic studies exhibited ongoing denervation and chronic reinnervation changes involving the left lower limb...
Charcot-Marie-Tooth (CMT) neuropathy remains one of the most common and genetically diverse neuromuscular disorders within the neurologic field. Mutations in >120 genes reflect the genetic heterogeneity of CMT, the most common form being attributable to a PMP22 gene duplication (type 1a; CMT1A). CMT is broadly classified by inheritance type (dominant, recessive, or X-linked) and electrophysiology (demyelinating with upper limb motor conduction velocities 35–45 m/s).1 A distal pattern of generall...
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