A Fast Separation Method for Isotope Analysis Based on Compressed Nitrogen Gas and Ion-Exchange Chromatography Technique—A Case Study of Sr-Nd Isotope Measurement

High-purity N2 was used to increase the mobile phase flow rate during ion purification of ion-exchange resin. This was performed to improve the efficiency of isotope separation and purification, and to meet the efficiency requirements of rapid multiple-collector-inductively coupled plasma mass spectrometry (MC-ICPMS) analysis. For Cu isotope separation, our results indicated that at a gas flow rate >60 mL/min, the separation chromatographic...