Development of Methods for the Mapping of Utilities Using Mixture Models: Mapping the AQLQ-S to the EQ-5D-5L and the HUI3 in Patients with Asthma

BackgroundStudies have shown that methods based on mixture models work well when mapping clinical to preference-based methods.ObjectivesTo develop these methods in different ways and to compare performance in a case study.MethodsData from 856 patients with asthma allowed mapping between the Asthma Quality of Life Questionnaire and both the five-level EuroQol five-dimensional questionnaire (EQ-5D-5L) and the health utilities index mark 3 (HUI3)....