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Mónica Hernández Alava
University of Sheffield
StatisticsPhysical therapyEQ-5DMedical encyclopediaMedicine
63Publications
13H-index
526Citations
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Publications 64
Newest
#1Mónica Hernández Alava (University of Sheffield)H-Index: 13
#2Stephen Pudney (University of Sheffield)H-Index: 24
Last. Allan Wailoo (University of Sheffield)H-Index: 31
view all 3 authors...
Abstract Objectives Five-level EuroQol 5-dimensional questionnaire (EQ-5D-5L) values for several countries now exist. Decision makers require confidence in the underlying data and statistical analyses before advocating their use. Independent quality assurance of the published English value set is reported here. Methods Data from 996 participants, and code to run published statistical models, were provided for inspection. The main elements of the study were 10 lead-time trade-off (TTO) experiment...
1 CitationsSource
#1Ali Kiadaliri (Lund University)H-Index: 1
#2Mónica Hernández Alava (University of Sheffield)H-Index: 13
Last. Martin Englund (BU: Boston University)H-Index: 49
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Purpose To develop a mapping model to estimate EQ-5D-3L from the Knee Injury and Osteoarthritis Outcome Score (KOOS).
Source
#2Allan WailooH-Index: 31
Last. A. Manca
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#1Laura A. Gray (University of Sheffield)H-Index: 4
#2Allan Wailoo (University of Sheffield)H-Index: 31
Last. Mónica Hernández Alava (University of Sheffield)H-Index: 13
view all 3 authors...
Abstract Background Preference-based measures of health, such as the three-level EuroQol five-dimensional questionnaire (EQ-5D-3L), are required to calculate quality-adjusted life-years for use in cost-effectiveness analysis, but are often not recorded in clinical studies. In these cases, mapping can be used to estimate preference-based measures. Objectives To model the relationship between the EQ-5D-3L and the Functional Assessment of Cancer Therapy—Breast Cancer (FACT-B) instrument, comparing ...
2 CitationsSource
#1Laura A. Gray (University of Sheffield)H-Index: 4
#2Mónica Hernández Alava (University of Sheffield)H-Index: 13
Last. Michael J. Campbell (University of Sheffield)H-Index: 74
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The prevalence of childhood obesity has been increasing but the causes are not fully understood. Recent public health interventions and guidance aiming to reduce childhood obesity have focused on the whole family, as opposed to just the child but there remains a lack of empirical evidence examining this relationship. Using data from the longitudinal Millennium Cohort Study (MCS), we investigate the dynamic relationship between underlying family lifestyle and childhood obesity during early childh...
6 CitationsSource
#1Mónica Hernández Alava (University of Sheffield)H-Index: 13
#2Allan Wailoo (University of Sheffield)H-Index: 31
Last. Lisa Irvine (UEA: University of East Anglia)H-Index: 10
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Objectives: To model the relationship between the three-level (3L) and the five-level (5L) EuroQol five-dimensional questionnaire and examine how differences have an impact on cost-effectiveness in case studies. Methods: We used two data sets that included the 3L and 5L versions from the same respondents. The EuroQol Group data set (n = 3551) included patients with different diseases and a healthy cohort. The National Data Bank data set included patients with rheumatoid disease (n = 5205). We es...
24 CitationsSource
#1Laura A. Gray (University of Sheffield)H-Index: 4
#2Mónica Hernández Alava (University of Sheffield)H-Index: 13
In this article, we describe the betamix command, which fits mixture regression models for dependent variables bounded in an interval. The model is a generalization of the truncated inflated beta regression model introduced in Pereira, Botter, and Sandoval (2012, Communications in Statistics—Theory and Methods 41: 907–919) and the mixture beta regression model in Verkuilen and Smithson (2012, Journal of Educational and Behavioral Statistics 37: 82–113) for variables with truncated supports at ei...
4 CitationsSource
#1Laura A. Gray (University of Sheffield)H-Index: 4
#2Mónica Hernández Alava (University of Sheffield)H-Index: 13
Last. Allan Wailoo (University of Sheffield)H-Index: 31
view all 3 authors...
Abstract Background Studies have shown that methods based on mixture models work well when mapping clinical to preference-based methods. Objectives To develop these methods in different ways and to compare performance in a case study. Methods Data from 856 patients with asthma allowed mapping between the Asthma Quality of Life Questionnaire and both the five-level EuroQol five-dimensional questionnaire (EQ-5D-5L) and the health utilities index mark 3 (HUI3). Adjusted limited dependent variable m...
6 CitationsSource
#1Gordon Fuller (University of Sheffield)H-Index: 15
#2Mónica Hernández Alava (University of Sheffield)H-Index: 13
Last. Belinda J. Gabbe (Alfred Hospital)H-Index: 51
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Abstract Background Valid and relevant estimates of health state preference weights (HSPWs) for Glasgow Outcome Scale (GOS) categories are a key input of economic models evaluating treatments for traumatic brain injury (TBI). Objectives To characterize existing HSPW estimates, and model the EuroQol five-dimensional questionnaire (EQ-5D) from the GOS, to inform parameterization of future economic models. Methods A systematic review of HSPWs for GOS categories following TBI was conducted using a h...
5 CitationsSource
Last. Allan WailooH-Index: 31
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Objectives: To develop methods for mapping to preference-based measures using mixture model approaches. These methods are compared to map from the Asthma Quality of Life Questionnaire (AQLQ) to both EQ5D-5L and HUI-3 as the target health utility measures in an international dataset. Methods: Data from 856 patients with asthma collected as part of the Multi-Instrument Comparison (MIC) international project were used. Adjusted limited dependent variable mixture models (ALDVMMs) and beta-regression...
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