Original paper

Serum neurofilament light in familial Alzheimer disease

Volume: 89, Issue: 21, Pages: 2167 - 2175
Published: Nov 21, 2017
Abstract

Objectives:

To investigate whether serum neurofilament light (NfL) concentration is increased in familial Alzheimer disease (FAD), both pre and post symptom onset, and whether it is associated with markers of disease stage and severity.

Methods:

We recruited 48 individuals from families with PSEN1 or APP mutations to a cross-sectional study: 18 had symptomatic Alzheimer disease (AD) and 30 were asymptomatic but at...
Paper Details
Title
Serum neurofilament light in familial Alzheimer disease
Published Date
Nov 21, 2017
Journal
Volume
89
Issue
21
Pages
2167 - 2175
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