Original paper
Downregulated apoptosis and autophagy after anti‐Aβ immunotherapy in Alzheimer's disease
Abstract
Aβ immunization of Alzheimer's disease (AD) patients in the AN1792 (Elan Pharmaceuticals) trial caused Aβ removal and a decreased density of neurons in the cerebral cortex. As preservation of neurons may be a critical determinant of outcome after Aβ immunization, we have assessed the impact of previous Aβ immunization on the expression of a range of apoptotic proteins in post‐mortem human brain tissue. Cortex from 13 AD patients immunized with...
Paper Details
Title
Downregulated apoptosis and autophagy after anti‐Aβ immunotherapy in Alzheimer's disease
Published Date
Feb 6, 2018
Journal
Volume
28
Issue
5
Pages
603 - 610
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Notes
History