Review paper
Engineering nanomaterials to overcome the mucosal barrier by modulating surface properties
Abstract
Although nanotechnology has been investigated during recent years to increase the bioavailability and therapeutic effects of mucosal administrated drugs, numerous barriers (e.g., pH environment, enzymes and mucus) still limit the delivery efficiency. And the epithelium would also affect the systemic mucosal drug delivery. Amongst all the barriers, the protective mucus has drawn more and more attention, which strongly hinders the accessibility of...
Paper Details
Title
Engineering nanomaterials to overcome the mucosal barrier by modulating surface properties
Published Date
Jan 1, 2018
Volume
124
Pages
150 - 163
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