Intraperitoneal injection of d -serine inhibits high-fat diet intake and preference in male mice

Volume: 118, Pages: 120 - 128
Published: Nov 1, 2017
Abstract
d-serine is a co-agonist of the N-methyl d-aspartate (NMDA) receptor, an important modulator of glutamatergic excitatory synaptic transmission. We previously reported that oral d-serine ingestion inhibited the intake of highly preferred food and promoted the intake of less preferred food in mice. Here, we analyzed the effects of intraperitoneal (IP) d-serine injections on feeding behavior in mice. We assessed the effects of d-serine during both...
Paper Details
Title
Intraperitoneal injection of d -serine inhibits high-fat diet intake and preference in male mice
Published Date
Nov 1, 2017
Journal
Volume
118
Pages
120 - 128
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