E-selectin and sICAM-1, biomarkers of endothelial function, predict recurrence of venous thromboembolism

Background Risk factors for atherosclerosis and venous thromboembolism (VTE) overlap and are mostly associated with endothelial dysfunction (ED). We hypothesized that ED is present in patients after the first episode of acute pulmonary embolism (APE) and predicts the risk of VTE recurrence. Design and Methods: Patients, at least 6 months after the first episode of symptomatic, confirmed APE were included in this case-control study. The exclusion...