Redox Signals in Healthspan and Metabolic Disease

Processing and intermediate metabolism of macronutrients are essential components of any life. Facultative or obligatory conversion of carbohydrates as well as fatty and amino acids into readily available energy equivalents like ATP are tightly regulated. Our interest is focused on the role of specific amino acids and glucose metabolites on nematodal and murine lifespan. Downstream oxidative metabolism of fatty and amino acids, as well as...