18F-FDG as an inflammation biomarker for imaging dengue virus infection and treatment response
Abstract
Development of antiviral therapy against acute viral diseases, such as dengue virus (DENV), suffers from the narrow window of viral load detection in serum during onset and clearance of infection and fever. We explored a biomarker approach using 18F-fluorodeoxyglucose (18F-FDG) PET in established mouse models for primary and antibody-dependent enhancement infection with DENV. 18F-FDG uptake was most prominent in the intestines and correlated...
Paper Details
Title
18F-FDG as an inflammation biomarker for imaging dengue virus infection and treatment response
Published Date
May 4, 2017
Journal
Volume
2
Issue
9
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