(120) Diet and bioactive lipid mediators for treatment of chronic pain: a translational approach

As key components of cellular membranes, fatty acids and their bioactive lipid mediator derivatives are uniquely positioned to impact chronic pain. A small clinical trial performed in our laboratory found that increasing omega-3 (n-3) PUFA and decreasing omega-6 (n-6) PUFA (H3L6 diet) caused decreases in headaches and improvements in quality of life in chronic daily headache sufferers.1 These clinical improvements were accompanied by increases...