The diverse family of M mpL transporters in mycobacteria: from regulation to antimicrobial developments
Abstract
Summary Mycobacterial genomes contain large sets of loci encoding membrane proteins that belong to a family of multidrug resistance pumps designated Resistance‐Nodulation‐Cell Division (RND) permeases. Mycobacterial membrane protein Large (MmpL) transporters represent a subclass of RND transporters known to participate in the export of lipid components across the cell envelope. These surface‐exposed lipids with unusual structures play key roles...
Paper Details
Title
The diverse family of M mpL transporters in mycobacteria: from regulation to antimicrobial developments
Published Date
Apr 18, 2017
Journal
Volume
104
Issue
6
Pages
889 - 904
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