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An overview of chemical constituents from Alpinia species in the last six decades

Published on Jan 1, 2017in RSC Advances3.05
· DOI :10.1039/C6RA27830B
Xiao-Ni Ma2
Estimated H-index: 2
(SOA: State Oceanic Administration),
Chun-Lan Xie4
Estimated H-index: 4
(SOA: State Oceanic Administration)
+ 2 AuthorsXian-Wen Yang23
Estimated H-index: 23
(SOA: State Oceanic Administration)
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Abstract
Alpinia species is one of the most important genera of the Zingiberaceae family. In Asia, they have been widely used as food and traditional medicines for centuries. This review focuses on their chemical constituents and their relevant biological activities with 252 references covering from 1955 to 2015. In total, 544 compounds were isolated from 35 Alpinia species. The major ones are terpenoids (207) and diarylheptanoids (143). The crude extracts and identified compounds exhibited a broad spectrum of bioactivities including antiemetic, antiulcer, antibacterial, anti-inflammatory, anti-amnesic, anticancer, etc.
  • References (210)
  • Citations (4)
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References210
Newest
Published on Sep 1, 2016in Chinese Journal of Integrative Medicine1.45
Chinthamony Arul Raj4
Estimated H-index: 4
(Karpagam University),
Paramasivam Ragavendran6
Estimated H-index: 6
(Karpagam University)
+ 3 AuthorsVelliyur Kanniappan Gopalakrishnan13
Estimated H-index: 13
(Karpagam University)
Objective To evaluate the enzymatic and non-enzymatic antioxidants of leaf extract from Alpinia purpurata.
Published on Nov 1, 2015in Journal of Integrative Medicine
Eric Wei Chiang Chan12
Estimated H-index: 12
(UCSI University),
Siu Kuin Wong6
Estimated H-index: 6
(Monash University)
In this review, the phytochemistry and pharmacology of two ornamental gingers, Hedychium coronarium (butterfly ginger) and Alpinia purpurata (red ginger), are updated, and their botany and uses are described. Flowers of H. coronarium are large, showy, white, yellow or white with a yellow centre and highly fragrant. Inflorescences of A. purpurata are erect spikes with attractive red or pink bracts. Phytochemical investigations on the rhizomes of H. coronarium generated research interest globally....
Published on Oct 14, 2015in Molecules3.06
de Sousa Dp36
Estimated H-index: 36
,
P.A.S. Hocayen3
Estimated H-index: 3
+ 1 AuthorsRoberto Andreatini28
Estimated H-index: 28
The clinical efficacy of standardized essential oils (such as Lavender officinalis), in treating anxiety disorders strongly suggests that these natural products are an important candidate source for new anxiolytic drugs. A systematic review of essential oils, their bioactive constituents, and anxiolytic-like activity is conducted. The essential oil with the best profile is Lavendula angustifolia, which has already been tested in controlled clinical trials with positive results. Citrus aurantium ...
Published on Oct 1, 2015in Fitoterapia2.43
Chuan-Pu Shen3
Estimated H-index: 3
(CPU: China Pharmaceutical University),
Jian-Guang Luo23
Estimated H-index: 23
(CPU: China Pharmaceutical University)
+ 1 AuthorsLing-Yi Kong36
Estimated H-index: 36
(CPU: China Pharmaceutical University)
Two pairs of enantiomers of flavonoid oligomers (1a and 1b, 2a and 2b) along with one known chalcone (3) were isolated from the rhizomes of Alpinia platychilus. Their structures were elucidated on the basis of spectroscopic data (MS and 1D/2D NMR). The absolute configurations of the flavonoid oligomers were established by their ECD spectra. Separation of the enantiomeric mixtures (1a and 1b, 2a and 2b) was achieved on a chiral column using hexane:isopropyl alcohol:ethanol (7:2:1) as eluents. The...
Published on Sep 9, 2015in Molecules3.06
Tran Dang Xuan25
Estimated H-index: 25
,
Rolf Teschke34
Estimated H-index: 34
Dihydro-5,6-dehydrokavain (DDK) is the major and most promising component of the tropical plant Alpinia zerumbet (shell ginger), a species of the ginger family Zingiberaceae. Alpinia zerumbet is known for its human use as a traditional herbal medicine, food, and dietary supplement. With its α-lactone ring, DDK belongs to the large chemical group of kavalactones, which are also found in kava (Piper methysticum), another herbal medicine; DDK is characterized by a double-bond linkage at positions 5...
Published on Aug 3, 2015in Journal of Asian Natural Products Research1.17
Wan-Qiu Yang1
Estimated H-index: 1
(Kunming University),
Yuan Gao1
Estimated H-index: 1
+ 2 AuthorsFei Wang26
Estimated H-index: 26
Three novel chalcones bearing a long-chain alkylphenol, galanganones A–C (1–3), were isolated from the rhizomes of Alpinia galanga. Their structures were elucidated by extensive spectroscopic analysis including 2D NMR experiments. Compounds 1–3 represent the first examples of long-chain alkylphenol-coupled chalcone.
Published on Jun 1, 2015in Weed Biology and Management1.00
Rachsawan Mongkol2
Estimated H-index: 2
(Chula: Chulalongkorn University),
Warinthorn Chavasiri19
Estimated H-index: 19
(Chula: Chulalongkorn University)
+ 2 AuthorsMasanori Morimoto8
Estimated H-index: 8
(Kindai University)
The management of weeds and diseases that are caused by phytopathogenic fungi is important for preventing the loss of agricultural products. The aim of the present study was to identify phytotoxic and antiphytopathogenic agents from the Thai Alpinia galanga rhizome. Extracts of the dried rhizomes of A. galanga (Zingiberaceae) were separated and tested for phytotoxic activity against lettuce (Lactuca sativa L. cv. Great Lakes) and Italian ryegrass (Lolium multiflorum Lam. cv. Wasefudou) and for a...
Published on Feb 1, 2015in Physiology & Behavior2.63
Shaohuai Shi3
Estimated H-index: 3
(SPU: Shenyang Pharmaceutical University),
Xu Zhao15
Estimated H-index: 15
(SPU: Shenyang Pharmaceutical University)
+ 5 AuthorsYing Jia15
Estimated H-index: 15
(SPU: Shenyang Pharmaceutical University)
Abstract Alzheimer's disease (AD) is one of the major neurological diseases of the elderly. How to safely and effectively remove the toxic Aβ42 peptide through blood–brain barrier (BBB) is considered to be an effective method for the prevention and treatment of AD. The compounds whose molecule weight is less than 400 Da and the number of hydrogen bonding is less than 10 are more likely to permeate BBB. In our previous study, we have several small molecule compounds which are isolated from n-buta...
Published on Feb 1, 2015in Applied Biochemistry and Biotechnology2.14
Sudipta Ghosh5
Estimated H-index: 5
(Indian Institute of Science Education and Research, Bhopal),
Latha Rangan13
Estimated H-index: 13
(IITG: Indian Institute of Technology Guwahati)
Current approach against type 2 diabetes involves α-glucosidase inhibitors like acarbose associated with many side effects. Therefore, as an alternative to the existing drug, many natural products mainly from plant sources have been investigated which inhibit α-glucosidase. Here, we have selected medicinally important Alpinia nigra to explore its α-glucosidase inhibitory activity. Organic extracts of seeds and two purified natural diterpenes I: (E)-labda-8(17), 12-diene-15, 16-dial and II: (E)-8...
Published on Jan 16, 2015in Molecules3.06
Lei Hou1
Estimated H-index: 1
,
Gang Ding2
Estimated H-index: 2
+ 4 AuthorsXiangfen Shi2
Estimated H-index: 2
The new compounds 2-methyl-6-isopropyl-7-hydroxymethyl naphthalene (1), oxyphyllenone H (2), epi-oxyphyllenone (6), (E)-labda-12,14-dien-15(16)-olide-17-oic acid (3), and two new natural products 4 and 5 were isolated from the ethyl acetate part of 95% ethanol extract of Alpinia oxyphylla, together with six known compounds 7–12. The inhibitory effects of compounds 1–12 on α-glucosidase were evaluated, and compounds 1, 3 and 6 showed moderate bioactive effect, with inhibitory rates of 10.3%, 10.0...
Cited By4
Newest
Published on 2019in Integrative Cancer Therapies2.63
Ching-Ying Kuo2
Estimated H-index: 2
(KMU: Kaohsiung Medical University),
Teng-Song Weng1
Estimated H-index: 1
(KMU: Kaohsiung Medical University)
+ 4 AuthorsHui-Chun Wang6
Estimated H-index: 6
(NSYSU: National Sun Yat-sen University)
Recent advances in mammography screening, chemotherapy, and adjuvant treatment modalities have improved the survival rate of women with breast cancer. Nevertheless, the breast tumor with metastatic...
Published on Oct 1, 2018in Toxicology and Applied Pharmacology3.58
Yasir Osman Ali Abdalla (UM: University of Malaya), Shaik Nyamathulla4
Estimated H-index: 4
(UM: University of Malaya)
+ 4 AuthorsNoor Hasima Nagoor9
Estimated H-index: 9
(UM: University of Malaya)
Abstract 1′-S-1′-acetoxychavicol acetate (ACA) has been previously reported to reduce tumor volume in nude mice, at an effective dose of 1.56 mg/kg body weight. However, the detailed toxicological profile for ACA has not yet been performed. Herein, we investigated the toxicity of intravenous administration of ACA in male and female Sprague-Dawley rats, both acutely (with single doses of 2.00, 4.00 and 6.66 mg/kg body weight, for 14 days), and sub-acutely (with weekly injections of 0.66, 1.33, an...
Published on Jun 1, 2018in Natural Product Communications0.55
Takashi Kamada7
Estimated H-index: 7
(UMS: Universiti Malaysia Sabah),
Shean-Yeaw Ng1
Estimated H-index: 1
(UMS: Universiti Malaysia Sabah)
+ 1 AuthorsCharles Santhanaraju Vairappan5
Estimated H-index: 5
(UMS: Universiti Malaysia Sabah)
Published on Jan 31, 2018in Nutrients4.17
Rolf Teschke34
Estimated H-index: 34
,
Tran Dang Xuan25
Estimated H-index: 25
The longevity of the population in the Okinawa Islands of Japan has been ascribed to genetic factors and the traditional Okinawa cuisine, which is low in calories and high in plant content. This diet includes shell ginger (Alpinia zerumbet (Pers.) B.L. Burtt & R.M. Sm) of the ginger family (Zingiberaceae). Due to its local popularity, Alpinia zerumbet has become the subject of a good deal of study at the University of the Ryukyus in Okinawa. Personal local experience and review of the literature...
Published on Dec 1, 2017in Bioorganic & Medicinal Chemistry Letters2.45
Richard D. McLane1
Estimated H-index: 1
(Northern Kentucky University),
Léon Le Cozannet-Laidin1
Estimated H-index: 1
+ 5 AuthorsAmber J. Onorato1
Estimated H-index: 1
(Northern Kentucky University)
Abstract Prostaglandin E 2 (PGE 2 ) is a lipid mediator of inflammation and its inhibition has become a popular drug target due to its harmful physiological roles. Diarylheptanoids are one class of compounds that have shown successful inhibition of PGE 2 . This paper reports the synthesis and PGE 2 inhibitory activity of a series of analogues of a naturally occurring diarylheptanoid. The most efficacious compounds were examined for dose-dependent PGE 2 inhibition. Among several promising compoun...
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