Original paper
De novo DNA methylation during monkey pre-implantation embryogenesis
Abstract
Critical epigenetic regulation of primate embryogenesis entails DNA methylome changes. Here we report genome-wide composition, patterning, and stage-specific dynamics of DNA methylation in pre-implantation rhesus monkey embryos as well as male and female gametes studied using an optimized tagmentation-based whole-genome bisulfite sequencing method. We show that upon fertilization, both paternal and maternal genomes undergo active DNA...
Paper Details
Title
De novo DNA methylation during monkey pre-implantation embryogenesis
Published Date
Feb 24, 2017
Journal
Volume
27
Issue
4
Pages
526 - 539
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Notes
History