Molecular characteristics of hepatocellular carcinomas (HCC) from different age groups

HCC patients (pts) from the Western hemisphere are usually diagnosed in their 50s and 60s, whereas HCCs in young adults (YA, 18-39 years) and the elderly (E, >75 years) are less common. Worldwide, HCCs diagnosed at extremes of the age spectrum are associated with distinct geography and etiologies. Multiplatform profiling data were used to compare molecular characteristics of HCCs of different age groups. Gene sequencing, amplification and...