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The effects of synthetic cannabinoids on executive function

Published on Apr 1, 2017in Psychopharmacology3.424
· DOI :10.1007/s00213-017-4546-4
K Cohen1
Estimated H-index: 1
(ELTE: Eötvös Loránd University),
Máté Kapitány-Fövény10
Estimated H-index: 10
(Semmelweis University)
+ 4 AuthorsAviv Weinstein27
Estimated H-index: 27
Abstract
Background and aims There is a growing use of novel psychoactive substances (NPSs) including synthetic cannabinoids. Synthetic cannabinoid products have effects similar to those of natural cannabis but the new synthetic cannabinoids are more potent and dangerous and their use has resulted in various adverse effects. The purpose of the study was to assess whether persistent use of synthetic cannabinoids is associating with impairments of executive function in chronic users.
  • References (69)
  • Citations (17)
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References69
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#1Francesca M. Filbey (UTD: University of Texas at Dallas)H-Index: 29
#2Tim McQueeny (UTD: University of Texas at Dallas)H-Index: 3
Last. Ariel Ketcherside (UTD: University of Texas at Dallas)H-Index: 6
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Abstract Combined use of marijuana (MJ) and tobacco is highly prevalent in today’s population. Individual use of either substance is linked to structural brain changes and altered cognitive function, especially with consistent reports of hippocampal volume deficits and poorer memory performance. However, the combined effects of MJ and tobacco on hippocampal structure and on learning and memory processes remain unknown. In this study, we examined both the individual and combined effects of MJ and...
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Introduction and Aims Synthetic cannabinoid dependence and withdrawal are not well described in the literature. We aimed to report on the characteristics and treatment course of clients attending a detoxification service for support with synthetic cannabinoid withdrawal in Auckland, New Zealand. Design and Methods A retrospective audit of electronic and paper files for clients presenting for treatment in association with problematic synthetic cannabinoid use between May 2013 and May 2014 was con...
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#1Rachael I. RosnerH-Index: 1
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#1Justine Renard (Paris V: Paris Descartes University)H-Index: 3
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Last. Thérèse M. Jay (Paris V: Paris Descartes University)H-Index: 1
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Marijuana is the most widely used illicit drug among adolescents and young adults. Unique cognitive, emotional, and social changes occur during this critical period of development from childhood into adulthood. The adolescent brain is in a state of transition and differs from the adult brain with respect to both anatomy (e.g., neuronal connections and morphology) and neurochemistry (e.g., dopamine, GABA, and glutamate). These changes are thought to support the emergence of adult cerebral process...
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#1Taylor HatchardH-Index: 7
#2Peter A. FriedH-Index: 31
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There is a growing body of evidence that marijuana use during adolescence, a critical period in neurocognitive development, may have lasting detrimental impact on executive functioning. The Ottawa Prenatal Prospective Study (OPPS) has followed participants over 20 years, from birth to young adulthood, and has collected data on potentially confounding lifestyle variables, such as prenatal drug exposure and current drug use. In the present study, we report the effects of heavy adolescent onset mar...
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Smoking cannabis produces a diverse range of effects, including impairments in learning and memory. These effects are exerted through action on the endocannabinoid system, which suggests involvement of this system in human cognition. Learning and memory deficits are core symptoms of psychiatric and neurological disorders such as schizophrenia and Alzheimer’s disease, and may also be related to endocannabinoid dysfunction in these disorders. However, before new research can focus on potential tre...
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BACKGROUND - Synthetic cannabinoids in smoking mixtures (such as Spice) or as raw powder are sold for recreational use as an alternative to herbal cannabis (hashish and marijuana). Although clinical case studies have documented an array of side effects, there is also information available at Internet based drug discussion forums. AIM - Our study investigates experiences of side effects from use of synthetic cannabinoids, as described and anonymously shared on Swedish online discussion forums. ME...
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Twelve cases of suspected impaired driving are discussed in which the drivers who subsequently tested positive for synthetic cannabinoid drugs underwent a psychophysical assessment. The attitude of the drivers was described as cooperative and relaxed, speech was slow and slurred and coordination was poor. Pulse and blood pressure were generally elevated. Horizontal gaze nystagmus was assessed in nine of the subjects, but was present in only two. The most consistent indicator was a marked lack of...
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The word “cannabinoid” refers to every chemical substance, regardless of structure or origin, that joins the cannabinoid receptors of the body and brain and that have similar effects to those produ...
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#1Koby Cohen (Ariel University)H-Index: 8
#2Shiri Rosenzweig (Ariel University)
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Objective Chronic use of synthetic cannabinoids (SCs) has been associated with a wide range of negative consequences for health including psychotic and affective disturbances. Accumulating evidence indicates that cannabinoids use may be a risk factor for schizophrenia, and chronic natural cannabis users score higher than non-users on measures of schizotypal personality traits. However, little is known regarding the personality characteristics of SC users, especially in comparison with recreation...
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#2Serenella Tolomeo (NUS: National University of Singapore)H-Index: 2
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Abstract Cannabis is currently the most used illicit substance in the world with a global widespread distribution. Although its acute neurocognitive effects on human behaviour have been reported, there is a lack of robust analysis investigating the link, if any, between chronic cannabis use and neurocognitive function. A systematic review of the literature was conducted in order to identify relevant studies published from 2010 to 2019. A meta-analysis was performed on 13 selected studies testing...
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