Emodin, a compound with putative antidiabetic potential, deteriorates glucose tolerance in rodents

Emodin is found in remedies from Traditional Chinese Medicine. Since antihyperglycaemic action was observed in rodents, non-scientific sources advertise emodin intake as a natural cure for diabetes. Emodin was admixed to high fat-food of obese mice at two doses (2 and 5 g/kg; daily emodin uptake 103 and 229 mg/kg). Comparison was made to ad libitum fed and to food restricted control groups, the latter showing the same weight gain as the...