Review paper
Liver Cancer Cell of Origin, Molecular Class, and Effects on Patient Prognosis
Abstract
Primary liver cancer is the second leading cause of cancer-related death worldwide and therefore a major public health challenge. We review hypotheses of the cell of origin of liver tumorigenesis and clarify the classes of liver cancer based on molecular features and how they affect patient prognosis. Primary liver cancer comprises hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (iCCA), and other rare tumors, notably...
Paper Details
Title
Liver Cancer Cell of Origin, Molecular Class, and Effects on Patient Prognosis
Published Date
Mar 1, 2017
Journal
Volume
152
Issue
4
Pages
745 - 761
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